Forced Maneuvers
Similar to spirometry in cooperative humans, Buxco's Forced Maneuvers systems provide comprehensive pulmonary function data for preclinical applications. The systems – available for mouse, rat/guinea pig, and larger subjects – are highly-automated and include all necessary hardware and software.
For the FRC maneuver, subjects must be spontaneously-breathing. For other maneuvers, subjects may be ventilated (ventilator included) or spontaneously-breathing. Subjects are anesthetized.
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| Control panel and pressure/vacuum reservoirs |
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Chambers for rat/guinea pig and mouse |
Available maneuvers
- Resistance and Dynamic Compliance
- Boyle's Law FRC
- Fast Flow Volume
- Quasistatic Pressure Volume
- DLCO and Multi-breath DLCO (except mouse)
Features
- Preferred system for COPD research
- Software-driven system, highly-automated
- Fast-response valving, low dead space
- Complete a series of maneuvers in just minutes
- Determine FRC and other lung capacities
- Software reports FEV(x), FEF(x) and many other values
- Ability to study small rodents - even mice
- Direct measurement of lung resistance and dynamic compliance
- View results immediately, use overlays to compare repeated maneuvers
For more information, see Pulmonary Function Testing.