FRC Determination

Fast Flow-Volume test

Quasi-static Pressure-Volume

DLCO test

Pulmonary Function Testing

Pulmonary Function Testing covers a battery of tests commonly used with cooperative humans. Buxco's preclinical application of these tests involves a series of forced maneuvers on anesthetized subjects. Inflation of the lungs, occlusion, and slow and rapid evacuation of the lungs provide a range of diagnostic tools, particularly in the study of COPD and fibrosis.

In addition to spirometry-type data, Buxco's system can be used for DLCO studies (except for mice).

Reported parameters

• Resistance
• Compliance, various measures
• FEV(x)
• FEF(x)
• Forced Vital Capacity
• Functional Residual Capacity
• Other lung capacities
• Inspiratory time
• Expiratory time
• Peak inspiratory flow
• Peak expiratory pause
• Pressure at peak compliance
• Volume at peak compliance
• Coefficient of diffusion
• Lung diffusing capacity
• Others

Available for rodents and NHP's.